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THCO or THC-O acetate, a lab-crafted synthetic cousin of Delta-9 THC, offers a buzz 3 times as potent as Delta-8 THC. THC-O is latest (and greatest) hemp-derived cannabinoid cooked up from CBD with two parts Delta-8 and three parts Delta-9. THC-O is pure, unadulterated hemp that offers one of the most potent and powerful psychotropic highs on the legal market today.