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My wife has had dystonia for 10 years, giving her constant pain in her neck, shoulders and back. Over the years, she's tried many products from ibuprofen to topical products to relieve her pain. After trying the first CHILL gummie, she noticed her pain getting less within 20 minutes. She started with half of a gummie, and noticed some improvement, but one whole gummie really does the job. There is no "high", just pain relief.